Sample Reports

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Browse sample reports generated from fictional data. Each report follows the same structure you'll receive with your personal genetic results.

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Three clinically-grounded reports, each covering a different aspect of your genetic health. Preview any of them below.

Medication Safety Report — Full Sample

Medication Safety Report

Pharmacogenomic Analysis — DecodeMyBio

Report Date: February 12, 2026

Report ID: DMB-2026-SAMPLE

Risk Snapshot

M

Moderate Risk

Overall Medication Genetic Risk

0

Significant

3

Moderate

13

Genes Tested

Next step: Share this report with your prescriber before starting or changing any of the medications listed below.

90-Second Summary

Genes with findings

3 of 13

CYP2C19, CYP2D6, SLCO1B1

Medications affected

12+

Including clopidogrel, codeine, simvastatin

Risk level

Moderate

No significant findings; 3 moderate

Your results show altered enzyme activity in 3 pharmacogenes. This means your body may process certain medications differently than expected. None of your findings are classified as significant risk, but each one may warrant a dosing adjustment or alternative medication.

When This Report Matters

  • You are prescribed clopidogrel (Plavix) after a cardiac stent — your CYP2C19 result means the standard dose may be less effective.
  • Your doctor prescribes codeine for pain relief — your CYP2D6 result suggests reduced conversion to the active form.
  • You start simvastatin (Zocor) for cholesterol — your SLCO1B1 result indicates higher risk of muscle-related side effects at standard doses.

Clinician Pocket Summary

One-Page Clinical Reference

GeneDiplotypePhenotypeActivityKey MedicationsSuggested Action
CYP2C19*1/*2Intermediate Metabolizer1.0Clopidogrel, escitalopram, sertralineConsider alternative antiplatelet; adjust SSRI if needed
CYP2D6*1/*4Intermediate Metabolizer1.0Codeine, tramadol, amitriptylineAvoid codeine; consider alternative analgesic
SLCO1B1*1A/*5Decreased FunctionN/ASimvastatin, atorvastatinUse lower simvastatin dose or alternative statin

Detailed Gene Findings

CYP2C19

*1/*2Intermediate Metabolizer

moderateLevel A

You carry one reduced-function CYP2C19 allele. This enzyme activates clopidogrel and metabolizes several SSRIs. With intermediate metabolizer status, you may have reduced activation of clopidogrel and altered SSRI levels.

Affected Medications

Clopidogrel (Plavix)Escitalopram (Lexapro)Citalopram (Celexa)Sertraline (Zoloft)Voriconazole (Vfend)

Clinical Recommendation

CPIC recommends considering an alternative antiplatelet agent (e.g., prasugrel or ticagrelor) for CYP2C19 intermediate metabolizers requiring antiplatelet therapy. For SSRIs, consider dose adjustment or therapeutic drug monitoring.

CYP2D6

*1/*4Intermediate Metabolizer

moderateLevel A

You carry one non-functional CYP2D6 allele. CYP2D6 metabolizes approximately 25% of all prescribed drugs. As an intermediate metabolizer, you have reduced enzyme activity, which can affect both prodrug activation and drug clearance.

Affected Medications

Codeine (Tylenol #3)Tramadol (Ultram)Amitriptyline (Elavil)Nortriptyline (Pamelor)Ondansetron (Zofran)

Clinical Recommendation

CPIC recommends avoiding codeine in intermediate metabolizers due to reduced conversion to morphine and unpredictable analgesic response. Consider alternative analgesics. For tricyclic antidepressants, consider a 25% dose reduction.

SLCO1B1

*1A/*5Decreased Function

moderateLevel A

You carry one reduced-function SLCO1B1 allele (rs4149056 TC). SLCO1B1 encodes a transporter that moves statins into liver cells. Decreased function leads to higher statin blood levels, increasing the risk of myopathy (muscle pain and weakness).

Affected Medications

Simvastatin (Zocor)Atorvastatin (Lipitor)

Clinical Recommendation

CPIC recommends prescribing a lower dose of simvastatin (max 20 mg/day) or considering an alternative statin such as pravastatin or rosuvastatin, which are less affected by SLCO1B1 variation.

Other Genes Tested

These genes were analyzed and returned normal or expected results. No dosing changes are indicated based on current CPIC guidelines.

GeneDiplotypePhenotype
CYP2C9*1/*1Normal Metabolizer
CYP3A5*3/*3Poor Metabolizer
CYP1A2*1F/*1FNormal/High Inducer
CYP3A4*1/*1Normal Metabolizer
CYP2B6*1/*1Normal Metabolizer
DPYD*1/*1Normal Metabolizer
TPMT*1/*1Normal Metabolizer
NUDT15*1/*1Normal Metabolizer
UGT1A1*1/*1Normal Metabolizer
VKORC1-1639 G/GNormal Sensitivity

Medication Checklist

Medications checked against your genetic profile. Actionable items have a gene-drug interaction that may affect dosing or drug choice.

!

Clopidogrel (Plavix)

CYP2C19actionable
!

Escitalopram (Lexapro)

CYP2C19actionable
!

Citalopram (Celexa)

CYP2C19actionable
!

Sertraline (Zoloft)

CYP2C19actionable
!

Codeine (Tylenol #3)

CYP2D6actionable
!

Tramadol (Ultram)

CYP2D6actionable
!

Amitriptyline (Elavil)

CYP2D6actionable
!

Simvastatin (Zocor)

SLCO1B1actionable
!

Atorvastatin (Lipitor)

SLCO1B1actionable

Warfarin (Coumadin)

CYP2C9/VKORC1normal

Omeprazole (Prilosec)

CYP2C19normal

Ibuprofen (Advil, Motrin)

CYP2C9normal

Severe Drug Reaction Risk (HLA-B)

Screening for HLA-B variants linked to severe drug hypersensitivity reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Based on tag SNP proxies, not clinical HLA typing.

HLA-B*57:01Not Detected

Affected medication: abacavir (Ziagen)

No HLA-B*57:01 risk allele was detected via tag SNP screening. This suggests a lower risk of abacavir hypersensitivity. This result is based on a tag SNP proxy and does not replace clinical HLA typing.

HLA-B*15:02Not Detected

Affected medication: carbamazepine (Tegretol)

No HLA-B*15:02 risk allele was detected via tag SNP screening. This suggests a lower risk of carbamazepine-induced SJS/TEN. This result is based on a tag SNP proxy and does not replace clinical HLA typing.

HLA-B*58:01Not Detected

Affected medication: allopurinol (Zyloprim)

No HLA-B*58:01 risk allele was detected via tag SNP screening. This suggests a lower risk of allopurinol hypersensitivity. This result is based on a tag SNP proxy and does not replace clinical HLA typing.

Limitations

  • Consumer genotyping arrays test a subset of known pharmacogenomic variants. Rare or novel alleles may not be detected.
  • Structural variants (e.g., CYP2D6 gene deletions or duplications) cannot be reliably determined from array data.
  • This report does not account for phenoconversion — when concomitant medications inhibit or induce enzyme activity, effectively changing your metabolizer status.
  • Allele frequency databases may underrepresent certain populations, potentially affecting phenotype assignment accuracy.
  • Drug response depends on multiple factors beyond genetics, including age, weight, kidney/liver function, diet, and other medications.

Glossary

Diplotype
The combination of two alleles (one from each parent) for a specific gene. For example, CYP2C19 *1/*2 means you inherited a *1 allele from one parent and a *2 allele from the other.
Phenotype
The predicted functional status of an enzyme based on your diplotype. Common phenotypes include Normal Metabolizer, Intermediate Metabolizer, and Poor Metabolizer.
CPIC Level A
The highest level of clinical evidence for a drug-gene interaction, as classified by the Clinical Pharmacogenetics Implementation Consortium. Level A means genetic information should be used to change prescribing of the affected drug.

This is a sample report generated with fictional data for demonstration purposes. Your actual report will reflect your personal genetic results.

What's Inside Your Report

Every Medication Safety Report includes these sections, covering genes like CYP2C19 and CYP2D6, and medications like clopidogrel

Risk Snapshot

Your overall medication genetic risk — High, Moderate, or Low — with a clear next step on the first page.

90-Second Summary

Top findings in plain language with affected medications and what to discuss with your provider.

Clinician Pocket Summary

A one-page clinical reference your doctor or pharmacist can review in under 60 seconds.

Detailed Gene Findings

Full analysis of each gene with your diplotype, phenotype, affected drugs, and CPIC-backed recommendations.

Complete Gene Panel

All 13 pharmacogenes tested with results — including the ones that came back normal.

Severe Drug Reaction Risk (HLA-B)

Screening for HLA-B variants linked to life-threatening drug reactions — abacavir, carbamazepine, and allopurinol.

Medication Checklist

Every medication checked against your genetics, with brand names you recognize and actionable/normal status.

Limitations & Glossary

Transparent disclosure of what this report can and cannot tell you, plus definitions of key terms.

Built on CPIC Guidelines

Every finding in this report cites evidence from the Clinical Pharmacogenetics Implementation Consortium (CPIC) — the same guidelines used by hospitals and pharmacies worldwide. Only Level A (strong) and Level B (moderate) evidence is included.

For educational and informational purposes only. Not a substitute for clinical pharmacogenomic testing or medical advice. See our limitations page for details.

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Medical Disclaimer

DecodeMyBio provides informational pharmacogenomic reports only. This is not medical advice. Always consult your healthcare provider before making medication changes.