Sample Report
Sample Nutrition & Methylation Report
This is a complete Nutrition & Methylation Report generated from sample data. Your report will follow the same structure with your personal genetic results.
Sample Data — Not Your Results
DecodeMyBio
Nutrition & Methylation Report
Nutrigenomic analysis based on your DNA
Generated: February 21, 2026
Your DNA shows 5 nutrient areas to be aware of.
Your Top Nutrient Priorities
Mildly Reduced MTHFR Activity (A1298C)
Mildly Reduced Beta-Carotene Conversion
Lower COMT Activity (Met/Met)
Non-Secretor (Reduced B12 Absorption)
Less Active VDR (FokI ff)
Combined MTHFR Result
You carry variants in both MTHFR C677T (CT) and MTHFR A1298C (AC). This combination is sometimes called compound heterozygous. Published research suggests the combined effect of both variants on folate metabolism may be greater than either variant alone. Each variant individually has a modest effect on MTHFR enzyme activity, but together they can further reduce the enzyme’s ability to convert folic acid into its active form (methylfolate).
This finding is included in the detailed results below. The individual MTHFR C677T and A1298C findings describe each variant separately.
Detailed Results
Trait: Beta-Carotene Conversion
Your Genotype: CT
Result: Mildly Reduced Beta-Carotene Conversion
You carry one copy of the A379V variant. Research suggests this may reduce beta-carotene conversion efficiency by approximately 30%.
Considerations:
- Consider including preformed vitamin A sources (liver, eggs, dairy) in addition to plant-based carotenoids.
PMID:19103647
Trait: Catechol-O-Methyltransferase Activity
Your Genotype: AA
Result: Lower COMT Activity (Met/Met)
Your COMT result is Met/Met. You have lower COMT enzyme activity, meaning catecholamines (dopamine, norepinephrine) are broken down more slowly. This is associated with higher baseline catecholamine levels.
Considerations:
- Support stress management through regular physical activity and adequate sleep.
- Include magnesium-rich foods: nuts, seeds, and dark leafy greens.
PMID:15166467
Trait: Vitamin B12 Absorption
Your Genotype: AA
Result: Non-Secretor (Reduced B12 Absorption)
Your FUT2 result indicates non-secretor status. Research suggests non-secretors may have reduced vitamin B12 absorption through the gut, potentially leading to lower B12 levels over time.
Considerations:
- Include B12-rich foods regularly: meat, fish, eggs, dairy, and fortified cereals.
- Add fermented foods like yogurt and kefir for additional B12.
PMID:19706858
Trait: Folate Metabolism
Your Genotype: AC
Result: Mildly Reduced MTHFR Activity (A1298C)
You carry one copy of the A1298C variant. Research suggests this has a smaller effect on MTHFR activity than C677T and is generally not considered clinically significant on its own.
Considerations:
- Ensure adequate dietary folate intake.
- Prioritize folate-rich foods if both MTHFR variants are present.
PMID:14583803
Trait: Folate Metabolism
Your Genotype: CT
Result: Mildly Reduced MTHFR Activity
You carry one copy of the C677T variant. Research suggests this is associated with a modest reduction (~35%) in MTHFR enzyme activity. Most individuals with this genotype maintain adequate folate metabolism.
Considerations:
- Ensure adequate dietary folate from leafy greens, legumes, and fortified foods.
- Include B12, B6, and riboflavin sources: meat, fish, eggs, and whole grains.
PMID:25902009 PMID:22419726
Trait: Vitamin D Receptor Function
Your Genotype: TT
Result: Less Active VDR (FokI ff)
Your VDR FokI result indicates the ff genotype. Your vitamin D receptor produces a longer, less active protein. Research suggests this may require higher vitamin D levels to achieve the same signaling effect.
Considerations:
- Include vitamin D sources: fatty fish, egg yolks, and fortified foods.
- Consider vitamin D supplementation during winter months if sun exposure is limited.
PMID:22123492
Trait: Vitamin D Receptor Function
Your Genotype: CT
Result: Variant VDR (BsmI Carrier)
You carry one copy of the BsmI variant. Research suggests this may modestly influence vitamin D receptor sensitivity.
Considerations:
- Ensure adequate vitamin D through sunlight and diet — fatty fish, egg yolks, and fortified foods are good sources.
PMID:22123492
Action Plan
Priority 2 — Moderate Findings
- Consider including preformed vitamin A sources (liver, eggs, dairy) in addition to plant-based carotenoids.
- Support stress management through regular physical activity and adequate sleep.
- Include magnesium-rich foods: nuts, seeds, and dark leafy greens.
- Include B12-rich foods regularly: meat, fish, eggs, dairy, and fortified cereals.
- Add fermented foods like yogurt and kefir for additional B12.
Discuss these findings with your healthcare provider or a registered dietitian to determine which steps are most relevant for your situation.
Lab Tests to Discuss
Based on your genetic results, these tests may be useful to discuss with your provider:
- Homocysteine — related to folate and B12 metabolism
- Serum or RBC folate — measures folate status directly
- Serum B12 — measures vitamin B12 levels
- 25-OH Vitamin D — measures vitamin D status
What This Report Does Not Cover
- This is not a diagnosis of any nutrient deficiency or medical condition.
- This is not a meal plan or personalized dietary prescription.
- This report does not account for your medications, medical history, or lifestyle factors.
- Genetics is one input among many that affect nutrient needs — lab results and clinical context matter too.
Important Limitations
- Nutrigenomics is an evolving field. Research on gene-nutrient interactions continues to develop.
- Genetic variants are one factor among many that influence nutrient needs. Diet, lifestyle, health conditions, and medications all play a role.
- This report is for informational purposes only and does not constitute medical or dietary advice.
- Do not change your diet or supplement regimen based solely on this report. Consult a qualified healthcare provider or registered dietitian.
- Nutrient status depends on many factors beyond genetics, including absorption, diet quality, and overall health.
This is a sample report generated with fictional data for demonstration purposes. Your actual report will reflect your personal genetic results.
What's Inside Your Report
Every Nutrition & Methylation Report includes these sections, covering genes like MTHFR, BCMO1, COMT, FUT2, and VDR.
Priority Dashboard
Your top nutrient areas ranked by impact, with the genes and genotypes behind each finding.
MTHFR Compound Callout
If you carry variants in both MTHFR C677T and A1298C, a dedicated callout explains the combined effect on folate metabolism.
Detailed Findings
Each gene analyzed with your genotype, a plain-language explanation, and food-first considerations.
Action Plan
Tiered recommendations organized by priority, with food-first steps you can discuss with your provider.
Lab Tests to Discuss
Suggested blood tests to confirm your genetic findings with real-world nutrient levels.
Scope & Limitations
What this report covers, what it does not, and important caveats about nutrigenomic analysis.
Evidence-Based Nutrigenomics
Every finding in this report cites peer-reviewed research. Gene-nutrient associations are drawn from published studies and cross-referenced with your genotype data.
For educational and informational purposes only. Not a substitute for clinical testing or medical advice. See our limitations page for details.
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